Robertina di mike bongiorno biography
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Merkelcell polyomavirus detection in Merkelcell cancer tumors in Northern Germany using PCR and protein expression.
PubMed
Leitz, Miriam; Stieler, Kristin; Grundhoff, Adam; Moll, Ingrid; Brandner, Johanna M; Fischer, Nicole
2014-10-01
Merkelcell carcinoma is a highly malignant skin cancer which predominantly occurs in elderly and immunocompromised persons. The identification of the Merkelcell polyomavirus (MCPyV) has inaugurated a new understanding of Merkelcell carcinoma pathogenesis. The frequent detection of the virus in Merkelcell carcinoma tissue (70-90%), its monoclonal integration in the tumorcells and the expression of viral oncogenes highly suggest that MCPyV is causally linked to the pathogenesis of the majority of Merkelcell cancer (MCC) cases. Using qualitative and quantitative PCR together with immunohistochemical staining this study aimed at characterizing the presence of MCPyV sequences and viral early gene expression in a cohort of MCC cases (n = 32) selected in Northern Germany. 40-57% of the cases were identified as MCPyV positive with 40.6% of the cases positive by immunohistochemical staining and 51.6-57.6% positive by PCR. Interestingly, in the majority (64%) of LT-Antigen positive tumors only 25-50% of tumorcells express LT-Antigen. These data are in accord with published studies describing heterogeneity in MCPyV viral loads and suggest that detection of MCPyV in Merkelcell carcinoma by PCR should be undertaken using multiple primer pairs. © 2013 Wiley Periodicals, Inc.
MerkelCell Polyomavirus Small T Antigen Initiates MerkelCell Carcinoma-like Tumor Development in Mice.
PubMed
Verhaegen, Monique E; Mangelberger, Doris; Harms, Paul W; Eberl, Markus; Wilbert, Dawn M; Meireles, Julia; Bichakjian, Christopher K; Saunders, Thomas L; Wong, Sunny Y; Dlugosz, Andrzej A
2017-06-15
Merkelcell carcinoma (MCC) tumorcells express several markers detected in normal Merkelcells, a nonproliferative population of neuroendocrine cells that arise
Biography of Mino Reitano
biography • National themes of love
Beniamino Reitano, known as Mino, was born in Fiumare (Reggio Calabria) on December 7, 1944. He was orphaned by his mother, who died in childbirth at the age of 27. His father, Rocco (1917–1994), was a railway worker; in his spare time, he plays the clarinet and is the director of the Fiumare Music Group. Mino studied piano, violin and trumpet at the Reggio Conservatory for eight years.
At the age of ten, he was a guest on the TV program Carousel of Motives, presented by Silvio Gigli. He takes his first steps in his musical career, giving himself up to rock and roll with his brothers Antonio Reitano, Vincenzo (Ghege) Reitano and Franco Reitano (the name of the group varies from Fratelli Reitano, Franco Reitano & His Brothers, Beniamino and the Reitano Brothers), with them he participates in the Cassano Jonico Festival and the Calabrian Music Review.
He recorded his first single in '45: the disc contains the songs "Tu sei la luce" and "Non sei un angelo", which gave him the first paragraph in the national magazine TV Sorrisi e Canzoni (No. 1961 of August 32, 6, p.1961).
At the end of the same year, he moved to Germany, where the group is hired for a number of gigs, including a club where they play with the Beatles (at the time they were called "The Quarrymen" and were in their infancy). After a year and a half away from Italy, he returned in 1963 to publish his second single "Robertina twist" and third "Twist time", which, however, went unnoticed.
Then he continues to play in Germany, even in the famous Reeperbahn in Hamburg, and to publish in this country unreleased records in Italy under the name Beniamino. "
In 1965 he took part in the Castrocaro Festival, performing Roy Orbison's "It's Over" in English: he did not win, but reached the final.
After receiving a contract with Dischi Ricordi, he published La fine di tutto, an Italian version of It's over in 1966, and the following year made .